Intracerebroventricular administration of Pasipay, the hydroalcoholic extract of Passiflora incarnata, suppresses epileptic seizures in rats

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Effect of intracerebroventricular injection of olive leaf extract on PTZ-induced seizures in male rats

Introduction: Olive leaf contains anti-inflammatory and COX-2 inhibitor compounds. Considering the role of the COX enzyme in seizures, this research was performed to assess the effects of this extract in treatment of seizures induced by PTZ. Methods: In this research, male Wistar rats (200±20 g) were injected intra-cerebroventricularly with 1 μl saline or olive leaf extract (125 μg, 250 μg ...

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Effect of hydroalcoholic extract of ginger on the liver of epileptic female rats treated with lamotrigine

Objective: Lamotrigine is an antiepileptic drug, widely used in the treatment of epilepsy; long-term use of this drug can cause hepatotoxicity. Zingiber officinale Roscoe (ginger) possesses antioxidant properties. In present research, the effect ofhydroalcoholic extract of ginger (HEG) on the liver of lamotrigine-treated epileptic rats was investigated Material and Methods: Forty-eight female W...

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ژورنال

عنوان ژورنال: Annals of General Psychiatry

سال: 2008

ISSN: 1744-859X

DOI: 10.1186/1744-859x-7-s1-s222